Agilent Technologies Inc. (NYSE: A) has
introduced the Agilent SurePrint G3 Human Gene-Expression v2 Microarray, the
only product available with an array of probes designed using the Broad
Institute's recently published human reference catalog of large intergenic
noncoding RNAs.
LincRNAs are believed to be important
regulators of gene expression, playing a role in embryonic development and
other cellular processes. Functional analysis of individual lincRNAs has proved
challenging for researchers but recent advances in sequencing and computational
methods have improved analytic capabilities in the field.
"We've just begun to scratch the
surface of how lincRNAs control a host of processes in the body, from fat
development to tumor growth," said Moran N. Cabili, a researcher at the
Broad Institute and co-author of the article introducing the human lincRNA
reference catalog. "This collaboration with Agilent, which draws on the most
comprehensive database of lincRNAs created to date, will be instrumental in
speeding the discovery process."
"The SurePrint G3 Human Gene
Expression Microarray is the most up-to-date product available in the emerging
field of lincRNA research," said Kathleen Shelton, senior director,
Genomics at Agilent. "We are pleased to collaborate with the renowned
Broad Institute to develop cutting-edge probes that will advance the study of
how lincRNAs function in gene regulation."
Cabili will present a free webinar,
hosted by Agilent, titled "Finding the missing lincs of the
transcriptome," on June 6 at 8 a.m. PDT. Topics to be covered during the
webinar include the characterization of lincRNAs, expression patterns of
lincRNAs in specific tissues compared to coding gene expression, and the
potential roles of transcripts of uncertain coding potential. For more details
or registration, visit agilenteseminar.webex.com.
The SurePrint G3 Human Gene Expression
v2 Microarray is part of a highly sensitive microarray platform with the widest
dynamic range (over five orders of magnitude), designed to detect low and high
expressors. The new microarray system has fully customizable content, allowing
researchers to design microarrays relevant to their experiment.
In addition to the newly available
probes, the SurePrint G3 Human Gene Expression v2 Microarray includes an update
of the latest mRNA content from the National Center for Biotechnology
Information RefSeq gene database.
For more information, visit www.agilent.com/genomics/v2GExArray.
About Agilent Technologies
Agilent Technologies Inc. (NYSE: A) is
the world's premier measurement company and a technology leader in chemical
analysis, life sciences, electronics and communications. The company's 18,700
employees serve customers in more than 100 countries. Agilent had net revenues
of $6.6 billion in fiscal 2011. Information about Agilent is available at www.agilent.com.